Upcoming trial readouts

Phase 4 · Diffuse Astrocytoma, Anaplastic Astrocytoma

Phase 2 · B-Cell Malignancies

Phase 1/2 · Prostate Cancer

Phase 2 · Lung Cancer, Non-Small Cell

Phase 2 · Cervical Cancer, HPV-Related Carcinoma

Phase 2 · Atopic Dermatitis

Phase 1/2 · Advanced Solid Tumors

Phase 3 · Breast Cancer

Phase 2 · Overweight or Obesity

Phase 3 · Type 2 Diabetes Mellitus (T2DM)

Phase 3 · Type 2 Diabetes Mellitus (T2DM)

Phase 4 · Sciatica Acute, Lumbar Spinal Stenosis

Phase 2 · Glaucoma, Open-Angle, Ocular Hypertension

Phase 2/3 · Generalized Myasthenia Gravis

Phase 2 · Gastric Cancer, Gastroesophageal Junction Cancer

Phase 4 · Haemophilia A (Moderate or Severe), Hemophilia, Classic

Phase 2/3 · Small Cell Lung Cancer

Phase 2/3 · Prostate Cancer

Phase 3 · Sjögren's Syndrome

Phase 2/3 · ALK-Positive Non-Small Cell Lung Cancer (NSCLC)

Phase 2 · Duchenne Muscular Dystrophy

Phase 2 · Carcinoma, Non-Small-Cell Lung Cancer (NSCLC)

Phase 4 · Severe Hemophilia A, Moderate Hemophilia A

Phase 2 · Alzheimer's Disease

Phase 2 · Dermatitis, Atopic

Phase 3 · Endometrial Neoplasms

Phase 2 · Moderate to Severe Asthma

Phase 2 · Obesity

Phase 2 · Neoplasms, Colon

Phase 3 · Chickenpox

Phase 3 · Solid Tumors

Phase 1/2 · Metastatic Prostate Cancer

Phase 3 · Alzheimer Disease

Phase 2 · Pulmonary Hypertension, Heart Failure With Preserved Ejection Fraction

Phase 3 · Neoplasms

Phase 4 · COVID-19

Phase 2 · Parkinson's Disease (PD)

Phase 3 · Yellow Fever Immunization

Phase 3 · Menstrual Migraine

Phase 1/2 · Glioblastoma Multiforme

Phase 3 · Cancer

Phase 1/2 · Duchenne Muscular Dystrophy

Phase 1/2 · Multiple Myeloma

Phase 2 · Non-small Cell Lung Cancer

Phase 1/2 · Advanced MTAP-null Solid Tumors

Phase 1/2 · Glycogen Storage Disease

Phase 3 · APDS

Phase 3 · Leukocyte Adhesion Deficiency

Phase 1/2 · Metastatic Castration-resistant Prostate Cancer

Phase 1/2 · Mesial Temporal Lobe Epilepsy

Phase 2 · Eye Cancer, Primary Cancer

Phase 2 · Idiopathic Hypersomnia

Phase 2 · Narcolepsy Type 2

Phase 3 · Breast Cancer

Phase 1/2 · KRAS G12D Mutation, Advanced Solid Cancer

Phase 2 · Monkeypox (Mpox)

Phase 3 · Immune Thrombocytopenia

Phase 3 · Osteoarthritis Knee Pain

Phase 2 · Contraception

Phase 2 · Obesity and Cardiovascular Risk

Phase 4 · Healthy Volunteers

Phase 2 · Diffuse Large B-cell Lymphoma

Phase 1/2 · Colorectal Cancer, Pancreatic Cancer

Phase 1/2 · Cancer, Neoplasms

Phase 2 · Cushing Syndrome

Phase 3 · PAH, Pulmonary Hypertension

Phase 3 · Prostatic Neoplasms

Phase 3 · Chronic Stable Angina Pectoris

Phase 2 · Non-Muscle Invasive Bladder Cancer ("NMIBC") Unresponsive/Intolerant to BCG

Phase 2 · Lumbar Disc Disease

Phase 1/2 · Metastatic Breast Cancer

Phase 4 · Ulcerative Colitis

Phase 2/3 · Relapsed/Refractory Diffuse Large B-cell Lymphoma

Phase 2 · Solid Tumor

Phase 1/2 · Glioblastoma, Melanoma Stage IV

Phase 1/2 · Dry Age-related Macular Degeneration

Phase 2 · Solid Tumor, Adult, Cancer

Phase 2/3 · AMD, nAMD

Phase 2 · HER2 Positive Metastatic Breast Cancer

Phase 3 · Congenital Antithrombin Deficiency

Phase 3 · Primary Immunodeficiency Disease

Phase 2 · Metastatic Castration-Resistant Prostate Cancer

Phase 2/3 · Acute Stroke, Ischemic Stroke

Phase 2 · High-Grade Serous Ovarian, Fallopian Tube or Primary Peritoneal Cancer

Phase 2 · Progressive Fibrosing Interstitial Lung Disease (PF-ILD) / Progressive Pulmonary Fibrosis (PPF)

Phase 1/2 · Refractory Metastatic Colorectal Cancer, Solid Tumor

Phase 1/2 · Frontotemporal Dementia

Phase 3 · Platinum-resistant Ovarian Cancer, Platinum-refractory Ovarian Cancer

Phase 2 · Head and Neck Cancer, Squamous Cell Carcinoma of Oral Cavity

Phase 1/2 · Breast Neoplasms, Brain Neoplasms

Phase 3 · Hereditary Angioedema

Phase 2 · Multiple Myeloma

Phase 3 · Agitation, Alzheimer's Type Dementia

Phase 1/2 · HR+/HER2-negative Breast Cancer, Metastatic Breast Cancer

Phase 2 · Adenocarcinoma of Lung, Carcinoma, Non-Small-Cell Lung

Phase 1/2 · Lymphoma, B-Cell, Lymphoma, T-Cell

Phase 1/2 · Locally Advanced or Metastatic Solid Tumors, Non Small Cell Lung Cancer (NSCLC)

Phase 1/2 · LGLL - Large Granular Lymphocytic Leukemia, Primary Cutaneous Gamma-Delta T-Cell Lymphoma

Phase 3 · GEP-NET, Gastroenteropancreatic Neuroendocrine Tumor

Phase 3 · NASH, Cirrhosis, Liver

Phase 2 · Cerebral Amyloid Angiopathy

Phase 2 · Advanced Cholangiocarcinoma, FGFR2 Fusions

Phase 1/2 · Solid Tumor, Adult, Solid Tumor

Phase 2 · Type 1 Diabetes Mellitus With Hypoglycemia

Phase 3 · Fecal Incontinence

Phase 2 · Hypoxic-Ischemic Encephalopathy

Phase 1/2 · Solid Tumor, Biliary Tract Cancer

Phase 1/2 · Neuronal Ceroid Lipofuscinosis Type 2

Phase 2 · Lymphatic Malformation

Phase 1/2 · Lymphoblastic Lymphoma, T-Cell Lymphoblastic Leukemia/Lymphoma

Phase 2 · Major Depressive Disorder

Phase 1/2 · Heart Failure, Systolic

Phase 3 · Cholangiocarcinoma

Phase 2 · Endometrial Cancer, Endometrioid Tumor

Phase 2 · Systemic Lupus Erythematosus (SLE)

Phase 2 · Eosinophilic Granulomatosis With Polyangiitis, Churg-Strauss Syndrome

Phase 1/2 · ALL, Adult, AML, Adult

Phase 2 · Vulvar Diseases, HPV Infection

Phase 2 · Acute Pancreatitis

Phase 1/2 · Light Chain (AL) Amyloidosis

Phase 2 · Unresectable Metastatic Colorectal Cancer

Phase 1/2 · Arrhythmogenic Cardiomyopathy, PKP2-ACM

Phase 2/3 · Focal Epilepsy

Phase 1/2 · Solid Tumor

Phase 2 · NSCLC

Phase 1/2 · MRI Scan

Phase 3 · Glenohumeral Osteoarthritis

Phase 3 · Pulmonary Arterial Hypertension

Phase 1/2 · Advanced Solid Tumor

Phase 2 · Pressure Ulcer, Stage IV, Osteomyelitis

Phase 2 · Paroxysmal Nocturnal Hemoglobinuria

Phase 2 · Advanced Hepatocellular Carcinoma (HCC)

Phase 2 · Hearing Loss, Cochlear Trauma

Phase 2 · Steroid Refractory GVHD

Phase 3 · Acute Hereditary Angio Edema

Phase 1/2 · Advanced or Metastatic Solid Tumors, Breast Cancer

Phase 2 · Acute Ischemic Stroke

Phase 3 · Binge-Eating Disorder

Phase 2 · Myasthenia Gravis, Myasthenia Gravis, MuSK

Phase 2 · Basal Cell Carcinoma

Phase 1/2 · Melanoma Stage IV, Solid Tumor

Phase 2 · Focal Epilepsy

Phase 2 · Moderately to Severely Active Crohn Disease

Phase 3 · Hidradenitis Suppurativa

Phase 2 · Multifocal Motor Neuropathy

Phase 3 · Excessive Sleepiness, Shift-work Disorder

Phase 3 · Venous Leg Ulcer (VLU)

Phase 2 · Postmenopausal Osteoporosis

Phase 1/2 · Solid Tumor

Phase 2 · Myopia, Progressive

Phase 3 · Eosinophilic Esophagitis

Phase 2 · Refractory Metastatic Colorectal Cancer

Phase 1/2 · KRAS G12D Mutation

Phase 3 · Antibody-mediated Rejection

Phase 3 · Venous Leg Ulcer, Venous Ulcer

Phase 2/3 · Microvillus Inclusion Disease, Congenital Disorders

Phase 2 · Narcolepsy Type 1, Narcolepsy Type 2

Phase 1/2 · Type 1 Diabetes Mellitus, T1D

Phase 3 · Pneumococcal Infections

Phase 1/2 · Infertility, Male, Gene Abnormality

Phase 3 · Hereditary Angioedema (HAE)

Phase 2 · Chemotherapy Induced Neuropathic Pain, Chemotherapy Induced Pain Neuropathy

Phase 1/2 · oGHVD

Phase 3 · Meniere's Disease, Ménière's Disease

Phase 1/2 · Pandemic Influenza Immunization, Healthy Volunteers

Phase 2 · Retinitis Pigmentosa

Phase 3 · Androgenetic Alopecia, AGA

Phase 1/2 · Neurotrophic Keratitis

Phase 3 · Developmental and Epileptic Encephalopathy 1

Phase 3 · Dystrophic Epidermolysis Bullosa, DEB - Dystrophic Epidermolysis Bullosa

Phase 3 · Epileptic Encephalopathy, SCN2A Encephalopathy

Phase 2 · Non-obstructive Hypertrophic Cardiomyopathy

Phase 3 · Chronic Primary Immune Thrombocytopenia (ITP)

Phase 2 · Chronic Pruritus of Unknown Origin

Phase 3 · Viral Hepatitis

Phase 1/2 · Parkinson's Disease (PD)

Phase 2 · Nausea, Vomiting

Phase 2 · Invasive Mould Infection

Phase 3 · Social Anxiety Disorder (SAD)

Phase 2 · Cutaneous Lupus Erythematosus (CLE), Systemic Lupus Erythematosus

Phase 2 · Atopic Dermatitis (AD)

Phase 2 · Asthma

Phase 2 · Pulmonary Hypertension, Interstitial Lung Disease (ILD)

Phase 3 · Primary Vitreoretinal Lymphoma

Phase 3 · Nausea and Vomiting, Obesity

Phase 2 · RSV Infection, RSV

Phase 3 · Lung Cancer, Lung Metastases

Phase 2 · Hypertension, Acute Severe Hypertension

Phase 1/2 · Bipolar I Disorder

Phase 2/3 · Dry Eye Disease (DED)

Phase 2 · Asthma Acute, COPD Exacerbation Acute

Phase 3 · Postoperative Ocular Inflammation, Postoperative Ocular Pain

Phase 3 · Severe Alopecia Areata

Phase 2 · Non-Transfusion Dependent Beta-Thalassemia (NTDT)

Phase 2 · Alzheimer's Disease

Phase 3 · Lyme Disease

Phase 3 · Atrial Fibrillation

Phase 2 · Hidradenitis Suppurativa

Phase 3 · Psychosis Associated With Alzheimer's Disease

Phase 3 · Lung Cancer, Non-squamous, Non-small Cell

Phase 2 · Chronic Kidney Disease and Hypertension

Phase 2 · Primary Myelofibrosis

Phase 2 · Urothelial Carcinoma

Phase 4 · SARS-CoV-2

Phase 2 · Metastatic Castration-Resistant Prostate Cancer (mCRPC)

Phase 2 · Heart Failure

Phase 3 · Early-stage Non-squamous Non-small Cell Lung Cancer (NSCLC)

Phase 3 · Chickenpox

Phase 2 · Palmoplantar Pustulosis

Phase 2 · Overweight, Obesity

Phase 3 · Schizophrenia

Phase 1/2 · Advanced Solid Tumor, Advanced Malignant Neoplasm

Phase 2/3 · Polyradiculoneuropathy, Chronic Inflammatory Demyelinating

Phase 1/2 · Solid Tumor, Adult, Refractory Cancer

Phase 3 · Non-Clear Cell Renal Cell Carcinoma

Phase 3 · Generalized Myasthenia Gravis, gMG

Phase 2 · Locally Advanced Pancreatic Adenocarcinoma

Phase 3 · Moderate to Severe Glabellar Lines

Phase 3 · Moderate to Severe Glabellar Lines

Phase 3 · NMDAR Autoimmune Encephalitis, LGI1 Autoimmune Encephalitis

Phase 4 · Sensitive Skin

Phase 2 · Alzheimer Disease, Early Onset

Phase 2 · Crohn's Disease

Phase 2 · Ulcerative Colitis

Phase 3 · Narcolepsy Type 1 (NT1), Narcolepsy With Cataplexy

Phase 2/3 · Breast Cancer

Phase 2/3 · SCLC

Phase 3 · Hidradenitis Suppurativa

Phase 1/2 · Renal Cell Carcinoma

Phase 2 · Alzheimer Disease

Phase 2 · Geographic Atrophy

Phase 3 · Neovascular Age-Related Macular Degeneration (nAMD), Wet AMD

Phase 3 · Asthma

Phase 2 · Prostatic Neoplasm

Phase 1/2 · Non-Hodgkin Lymphoma

Phase 2 · Metastatic Castration-resistant Prostate Cancer

Phase 2 · Focal Segmental Glomerulosclerosis, Glomerulonephritis Minimal Lesion

Phase 3 · Chickenpox

Phase 2 · Chronic Spontaneous Urticaria

Phase 3 · Carcinoma, Ovarian Epithelial, Ovarian Neoplasms

Phase 3 · Hidradenitis Suppurativa (HS)

Phase 1/2 · Breast Cancer, Metastatic Breast Cancer

Phase 2 · Dry Eye Disease (DED)

Phase 2 · High-risk HPV (Any Strain), LSIL, Low Grade Squamous Intraepithelial Lesion

Phase 2 · Ovarian Neoplasms, Breast Neoplasms

Phase 2 · Anal High Grade Squamous Intraepithelial Lesion, Anal Precancerous Condition

Phase 2 · Hypercholesterolemia

Phase 3 · Tuberous Sclerosis Complex

Phase 2 · Hepatocellular Carcinoma, Gastric Cancer

Phase 3 · Renal Cell Carcinoma